Chemistry Reviews


25. The difference between the tertiary and quaternary levels of protein structure is that a tertiary level protein is one polypeptide chain with a complex, 3-D globular shape while a quaternary level protein is composed of 2 or more complex polypeptide chains which are bonded together to make a larger, globular protein.

The figure on the right is a tertiary level protein (1 complexly folded chain) while that on the right is a quaternary level protein (each of the 4 chains is colored differently).

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Slichter