[First Review of Proteins]

16. Why do temperatures above an enzyme's optimal temperature slow the enzyme's reaction rate?

A) The enzyme & substrate are moving so fast they get tired and stop to rest rather than react.

B) The enzyme is killed by high temperatures and can't react as well.

C) The enzyme is working so fast that all the substrate is used up and the reaction rate falls.

D) The active site becomes denatured so the substrate can't fit there, so the reaction slows down.

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Slichter