[Repiration Reviews]


9. Muscle cells must produce NAD+ as an end product of lactate fermentation so that glycolysis can continue to make a few ATP molecules.

NAD+ is needed as raw material during one of the intermediate steps of glycolysis. It accepts the energized electrons and hyrogen ions from the original glucose in steps which occur before any ATP is produced. If NAD+ is present, glycolysis continues to make ATP. If NAD+ isn't present, glycolysis shuts down and the muscle cell loses its source of ATP and would soon die!

 

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